姓名：赵恒
职务：无
职称：助教
学科：基础兽医导师类别： 无
电子邮箱：1553520031@qq.com
教育经历
(1) 2017-09 至 2020-06, 云南农业大学, 动物遗传育种与繁殖, 博士
(2) 2014-09 至 2017-06, 云南农业大学, 动物遗传育种与繁殖, 硕士
(3) 2010-09 至 2014-06, 云南农业大学, 动物科学, 学士
所授课程
无
工作经历
(1) 2020-12 至 今, 云南农业大学, 动物医学院,助教
研究领域与方向
1.基因编辑动物的制备
科研与教学
科研项目
（1）中华人民共和国科学技术部, 国家重点研发计划, 2019YFA0110700, 异种移植人源化基因编辑供体猪的构建及临床前研究, 2019-12 至 2023-12, 2771.00万元, 在研, 参与
(2) 国家自然科学基金委员会, 面上项目, 81872452, 自噬在紫杉醇抑制乳腺癌中的作用及其机制研究, 2019-01-01 至 2022-12-31, 57万元, 在研, 参与
(3) 国家自然科学基金委员会, 地区科学基金项目, 31660656, 调控猪卵母细胞Npm2表达的microRNAs的筛选及信号通路研究, 2017-01-01 至 2020-12-31, 39万元, 结题, 参与
教学项目
无
学术荣誉与奖励
无
代表性成果
代表性文章
1. Yin-Qiao Wu# , Heng Zhao# , Ying-Ju Li, Saber Khederzadeh, Hong-Jiang Wei, Zhong-Yin Zhou, Ya-Ping Zhang. Genome-wide identification of imprinted genes in pigs and their different imprinting status compared with other mammals. Zoological
Research.
2. Zhao, H# ., Li, Y., Wiriyahdamrong, T., Yuan, Z., Qing, Y., Li, H., Xu, K., Guo, J., Jia, B., Zhang, X., Cheng, W., Su, Y., Long, W., Wang, J., Zou, D., Kinoshita, K., Zhao, H. Y., & Wei, H. J. （2020）. Improved production of GTKO/hCD55/hCD59 triple-gene-modified Diannan miniature pigs for xenotransplantation by recloning. Transgenic research, 10.1007/s11248-020-00201-2.
3. Honghao Yu# , Weihu Long# , Xuezeng Zhang# , Kaixiang Xu, Jianxiong Guo, Heng Zhao, Honghui Li, Yubo Qing, Weirong Pan, Baoyu Jia, Hong-Ye Zhao, Xingxu Huang and Hong-Jiang Wei. Generation of GHR-modified pigs as Laron syndrome models via a dual-sgRNAs/Cas9 system and somatic cell nuclear transfer.Journal of Translational Medicine, 16(1): 41. 2018（IF: 3.786）
4. Sen Yan# , Zhuchi Tu, Zhaoming Liu, Nana Fan, Huiming Yang, Su Yang, Weili Yang, Yu Zhao, Zhen Ouyang, Chengdan Lai, Huaqiang Yang, Li Li, Qishuai Liu, Hui Shi, Guangqing Xu, Heng Zhao, Hongjiang Wei, Zhong Pei, Shihua Li*, Liangxue Lai*, and Xiao-Jiang Li*. A Huntingtin Knockin Pig Model Recapitulates Features of Selective Neurodegeneration in Huntington’s Disease. Cell, 173, 989–1002. 2018(IF:36.216).
5. Youfeng Shen# , Kaixiang Xu# , Zaimei Yuan, Jianxiong Guo, Heng Zhao, Xuezeng Zhang, Lu Zhao, Yubo Qing, Honghui Li, Weirong Pan, Baoyu Jia, Hong-Ye Zhao* and Hong-Jiang Wei* . Efficient generation of P53 biallelic knockout Diannan miniature pigs via TALENs and somatic cell nuclear transfer. Journal of Translational Medicine, 15:224-234. 2017(IF: 3.786).
6. Dong Niu# , Hongjiang Wei# , Lin Lin# , Haydy George# , Tao Wang# , I-Hsiu Lee# , Yong Wang, Yinan Kan, Ellen Shrock, Emal Lesha, Gang Wang, Yonglun Luo, YuboQing, Deling Jiao, Heng Zhao, Hongye Zhao, Xiaoyang Zhou, Shouqi Wang, Hong Wei, Marc Guell* , George M. Church* & Luhan Yang* . Inactivation of porcine endogenous retrovirus activity in pigs using CRISPR-Cas9. Science, 357: 1303-1307. 2017(IF:37.205).
7. Honghui Li# , Gui Wang# , Zhiqiang Hao# , GuoZhong Zhang, Yubo Qing, Shuanghui Liu, Lili Qing, Weirong Pan, Lei Chen, Guichun Liu, Ruoping Zhao, Baoyu Jia, Luyao Zeng, Jianxiong Guo, Lixiao Zhao, Heng Zhao, Chaoxiang Lv,Kaixiang Xu, Wenmin Cheng, Hushan Li, Hong-Ye Zhao*, Wen Wang*, Hong-Jiang Wei*. Generation of Biallelic Knock-out Sheep via Gene-editing and Somatic Cell Nuclear Transfer. Scientific reports. 6: 33675.
8. Honghao Yu# , Heng Zhao#, Yubo Qing, Weirong Pan, Baoyu Jia, Hong-Ye Zhao, Xingxu Huang*, Hong-Jiang Wei*. DMD-modified pig generated by injectingthe zygote with Cas9/sgRNA results in muscle dystrophy. International journal of molecular sciences, 17: 1668. 2016 (IF:3.257).
9. Wenmin Cheng# , Heng Zhao#, Honghao Yu, Jige Xin, Jia Wang, Luyao Zeng, Zaimei Yuan, Yubo Qing, Honghui Li, Baoyu Jia, Cejun Yang, Youfeng Shen, Lu Zhao，Weirong Pan, Hong-Ye Zhao* ,Wei Wang* , Hong-Jiang Wei* . Efficient generation of GGTA1-null Diannan miniature pigs using TALENs combined with somatic cell nuclear transfer. Reproductive biology and Endocrinology, Doi 10.1186/s12958-016-0212-7. 2016 (2.147).
著作
无。
专利
无。
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